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PDLIM7 Rabbit pAb

Cat No.: APA2806
Size:
Product Name: PDLIM7 Rabbit pAb
Cat No.: APA2806
source: Rabbit
reactivity: Human
applications: WB,IHC,FC
clonality: Polyclonal
recommended dilution: WB: 1:1000
IHC: 1:20
FC: 1:20
format: Liquid
isotype: IgG
immunogen: Recombinant protein of human PDLIM7
calculated molecular weight: 50 kDa
observed molecular weight: 50 kDa
genbank accession number: Q9NR12
gene id (ncbi): 9260
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: LMP1; LMP3
category: Primary Ab
concentration: 0.5mg/ml
background: The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
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