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HDAC6 Rabbit pAb

Cat No.: APA1005
Size:
Product Name: HDAC6 Rabbit pAb
Cat No.: APA1005
source: Rabbit
reactivity: Mouse, Rat
applications: WB, FC, IP
clonality: Polyclonal
recommended dilution: WB: 1:1000
FC: 1:200
IP: 1:20
format: Liquid
isotype: IgG
immunogen: A synthetic peptide of mouse HDAC6
calculated molecular weight: 126 kDa
observed molecular weight: 130 kDa
genbank accession number: Q9Z2V5
gene id (ncbi): 15185
purification method:
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: Hd6; Sfc6; Hdac5; mHDA2
category: Primary Ab
concentration: 0.5mg/ml
background: Enables cytoskeletal protein binding activity; protein deacetylase activity; and ubiquitin binding activity. Involved in several processes, including positive regulation of peptidyl-serine phosphorylation; protein deacetylation; and protein destabilization. Acts upstream of or within several processes, including aggresome assembly; cellular protein metabolic process; and neuron projection morphogenesis. Located in several cellular components, including dendrite; microtubule cytoskeleton; and perikaryon. Part of protein-containing complex. Is expressed in several structures, including central nervous system; early embryo; future midbrain; gut gland; and lung. Human ortholog(s) of this gene implicated in chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia. Orthologous to human HDAC6 (histone deacetylase 6). [provided by Alliance of Genome Resources, Apr 2022]