WAVE 1 Recombinant Rabbit mAb
Cat No.: ARM1787
| Product Name: | WAVE 1 Recombinant Rabbit mAb |
| Cat No.: | ARM1787 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,FC |
| clonality: | Monoclonal |
| recommended dilution: | WB,FC |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human WAVE 1 |
| calculated molecular weight: | 62 kDa |
| observed molecular weight: | 90 kDa |
| genbank accession number: | Q92558 |
| gene id (ncbi): | 8936 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | WAVE; SCAR1; WAVE1 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008] |
