GCLC Recombinant Rabbit mAb
Cat No.: ARM2038
Size：
| Product Name: | GCLC Recombinant Rabbit mAb |
| Cat No.: | ARM2038 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IP |
| clonality: | Monoclonal |
| recommended dilution: | WB,IP |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human GCLC |
| calculated molecular weight: | 73 kDa |
| observed molecular weight: | 73 kDa |
| genbank accession number: | P48506 |
| gene id (ncbi): | 2729 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | GCL; GCS; GLCL; GLCLC |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.[provided by RefSeq, Oct 2010] |