AHA1 Recombinant Rabbit mAb
Cat No.: ARM2496
| Product Name: | AHA1 Recombinant Rabbit mAb |
| Cat No.: | ARM2496 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IP |
| clonality: | Monoclonal |
| recommended dilution: | WB,IP |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human AHA1 |
| calculated molecular weight: | 38 kDa |
| observed molecular weight: | 42 kDa |
| genbank accession number: | O95433 |
| gene id (ncbi): | 10598 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | p38; AHA1; hAha1; C14orf3 |
| category: | Primary Ab |
| concentration: | 1mg/ml |
| background: | Acts as a co-chaperone of HSP90AA1 (PubMed:29127155). Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity (PubMed:29127155). Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360). Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:29127155). |
