Glutamate Receptor 1 Rabbit pAb
Cat No.: APA1416
| Product Name: | Glutamate Receptor 1 Rabbit pAb |
| Cat No.: | APA1416 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:20 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of mouse Glutamate Receptor 1 |
| calculated molecular weight: | 102 kDa |
| observed molecular weight: | 102 kDa |
| genbank accession number: | P23818 |
| gene id (ncbi): | 14799 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | Glr1; Glr-1; GluA1; GluRA; Glur1; HIPA1; GluR-A; Glur-1; gluR-K1; 2900051M01Rik |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. |
