ULBP1 Rabbit pAb
Cat No.: APA1498
| Product Name: | ULBP1 Rabbit pAb |
| Cat No.: | APA1498 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | FC |
| clonality: | Polyclonal |
| recommended dilution: | FC: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human ULBP1 |
| calculated molecular weight: | 28 kDa |
| observed molecular weight: | |
| genbank accession number: | Q9BZM6 |
| gene id (ncbi): | 80329 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | N2DL-1; RAET1I; NKG2DL1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The protein encoded by this gene is a ligand of natural killer group 2, member D (NKG2D), an immune system-activating receptor on NK cells and T-cells. Binding of the encoded ligand to NKG2D leads to activation of several signal transduction pathways, including those of JAK2, STAT5, ERK and PI3K kinase/Akt. Also, in cytomegalovirus-infected cells, this ligand binds the UL16 glycoprotein and is prevented from activating the immune system. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015] |
