Collagen II Rabbit pAb
Cat No.: APA1550
| Product Name: | Collagen II Rabbit pAb |
| Cat No.: | APA1550 |
| source: | Rabbit |
| reactivity: | Human, Rat |
| applications: | WB |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Collagen II |
| calculated molecular weight: | 142 kDa |
| observed molecular weight: | 30 kDa (Isoform 3) kDa |
| genbank accession number: | P02458 |
| gene id (ncbi): | 1280 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | AOM; ANFH; SEDC; STL1; COL11A3 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. [provided by RefSeq, Jul 2008] |
