Proteasome 20S alpha 5/PSMA5 Rabbit pAb
Cat No.: APA1585
| Product Name: | Proteasome 20S alpha 5/PSMA5 Rabbit pAb |
| Cat No.: | APA1585 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC,ICC/IF,FC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:50 ICC/IF: 1:20 FC: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Proteasome 20S alpha 5/PSMA5 |
| calculated molecular weight: | 26 kDa |
| observed molecular weight: | 26 kDa |
| genbank accession number: | P28066 |
| gene id (ncbi): | 5686 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | PSC5; ZETA |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010] |
