Caspase-2 Rabbit pAb
								Cat No.: APA1778
															
							
							| Product Name: | Caspase-2 Rabbit pAb | 
| Cat No.: | APA1778 | 
| source: | Rabbit | 
| reactivity: | Human | 
| applications: | WB | 
| clonality: | Polyclonal | 
| recommended dilution: | WB: 1:1000 | 
| format: | Liquid | 
| isotype: | IgG | 
| immunogen: | Recombinant protein of human Caspase-2 | 
| calculated molecular weight: | 51 kDa | 
| observed molecular weight: | 51 kDa | 
| genbank accession number: | P42575 | 
| gene id (ncbi): | 835 | 
| purification method: | Affinity Purification | 
| conjugate: | Un-conjugated | 
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. | 
| synonyms: | ICH1; NEDD2; CASP-2; NEDD-2; PPP1R57 | 
| category: | Primary Ab | 
| concentration: | 0.5mg/ml | 
| background: | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer--s disease, Huntington--s disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011] | 
				