Neurofilament heavy polypeptide Rabbit pAb
Cat No.: APA1865
Size：
| Product Name: | Neurofilament heavy polypeptide Rabbit pAb |
| Cat No.: | APA1865 |
| source: | Rabbit |
| reactivity: | Human, Mouse, Rat |
| applications: | WB,IHC |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IHC: 1:500 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Neurofilament heavy polypeptide |
| calculated molecular weight: | 113 kDa |
| observed molecular weight: | 180-220 kDa |
| genbank accession number: | P12036 |
| gene id (ncbi): | 4744 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | NFH; CMT2CC |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [provided by RefSeq, Oct 2008] |