Integrin alpha 4/CD49D Rabbit pAb
Cat No.: APA2065
| Product Name: | Integrin alpha 4/CD49D Rabbit pAb |
| Cat No.: | APA2065 |
| source: | Rabbit |
| reactivity: | Human, Mouse |
| applications: | WB |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human Integrin alpha 4/CD49D |
| calculated molecular weight: | 115 kDa |
| observed molecular weight: | 150,70 kDa |
| genbank accession number: | P13612 |
| gene id (ncbi): | 3676 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | IA4; CD49D |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 4 subunit. This subunit associates with a beta 1 or beta 7 subunit to form an integrin that may play a role in cell motility and migration. This integrin is a therapeutic target for the treatment of multiple sclerosis, Crohn--s disease and inflammatory bowel disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015] |
