GRK2 Rabbit pAb
Cat No.: APA2145
| Product Name: | GRK2 Rabbit pAb |
| Cat No.: | APA2145 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of human GRK2 |
| calculated molecular weight: | 80 kDa |
| observed molecular weight: | 80 kDa |
| genbank accession number: | P25098 |
| gene id (ncbi): | 156 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | BARK1; ADRBK1; BETA-ARK1 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer--s disease. [provided by RefSeq, Sep 2017] |
