IGF1 Receptor Rabbit pAb
Cat No.: APA2384
| Product Name: | IGF1 Receptor Rabbit pAb |
| Cat No.: | APA2384 |
| source: | Rabbit |
| reactivity: | Human |
| applications: | WB,ICC/IF,FC,IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 ICC/IF: 1:20 FC: 1:50 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | Recombinant protein of human IGF1 Receptor |
| calculated molecular weight: | 155 kDa |
| observed molecular weight: | 95 kDa |
| genbank accession number: | P08069 |
| gene id (ncbi): | 3480 |
| purification method: | Affinity Purification |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | IGFR; CD221; IGFIR; JTK13 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] |
