HDAC6 Rabbit pAb
Cat No.: APA1005
| Product Name: | HDAC6 Rabbit pAb |
| Cat No.: | APA1005 |
| source: | Rabbit |
| reactivity: | Mouse, Rat |
| applications: | WB, FC, IP |
| clonality: | Polyclonal |
| recommended dilution: | WB: 1:1000 FC: 1:200 IP: 1:20 |
| format: | Liquid |
| isotype: | IgG |
| immunogen: | A synthetic peptide of mouse HDAC6 |
| calculated molecular weight: | 126 kDa |
| observed molecular weight: | 130 kDa |
| genbank accession number: | Q9Z2V5 |
| gene id (ncbi): | 15185 |
| purification method: | |
| conjugate: | Un-conjugated |
| storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt. |
| synonyms: | Hd6; Sfc6; Hdac5; mHDA2 |
| category: | Primary Ab |
| concentration: | 0.5mg/ml |
| background: | Enables cytoskeletal protein binding activity; protein deacetylase activity; and ubiquitin binding activity. Involved in several processes, including positive regulation of peptidyl-serine phosphorylation; protein deacetylation; and protein destabilization. Acts upstream of or within several processes, including aggresome assembly; cellular protein metabolic process; and neuron projection morphogenesis. Located in several cellular components, including dendrite; microtubule cytoskeleton; and perikaryon. Part of protein-containing complex. Is expressed in several structures, including central nervous system; early embryo; future midbrain; gut gland; and lung. Human ortholog(s) of this gene implicated in chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia. Orthologous to human HDAC6 (histone deacetylase 6). [provided by Alliance of Genome Resources, Apr 2022] |
