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Vinculin Rabbit pAb

Cat No.: ATL1009
Product Name: Vinculin Rabbit pAb
Cat No.: ATL1009
source: Rabbit
reactivity: Human, Mouse, Rat
applications: WB,IHC,ICC/IF,FC,IP
clonality: Polyclonal
recommended dilution: WB: 1:2000
ICC/IF: 1:50
FC: 1:50
IP: 1:20
format: Liquid
immunogen: A synthetic peptide of human Vinculin
calculated molecular weight: 124 kDa
observed molecular weight: 124 kDa
genbank accession number: P18206
gene id (ncbi): 7414
purification method: Affinity Purification
conjugate: Un-conjugated
storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.
synonyms: MV; MVCL; CMD1W; CMH15; HEL114
category: Primary Ab
concentration: 0.5mg/ml
background: Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]